a A Proud to be a Banner Health Center of Excellence    Accessible View

Studies Currently Enrolling

For participants without memory loss
For participants with and without memory loss
For participants with memory loss

Brain Imaging, APOE & the Preclinical Course of Alzheimer’s Disease Study

ClinicalTrials.gov identifier: n/a

Ages Eligible for Study:

47-68 years

Genders Eligible for Study:


Accepts Healthy Volunteers:    



This study is sponsored by the National Institutes of Health (NIH) and is a long-term study that seeks to better understand the course of Alzheimer’s disease before clinical symptoms emerge. This brain imaging study, a collaboration with Mayo Clinic, will follow individuals indefinitely. The purpose is to observe the course of aging in participants with different genetic risk levels of developing different memory problems. The study includes visits every two years. Imaging visits include MRIs and PET scans. The study also includes optional lumbar punctures. Participants do not require a study partner.

Studies for participants without memory loss

GeneMatch: A Program of the Alzheimer's Prevention Registry to Match Individuals to Studies Based on Apolipoprotein E (APOE) Genotype (NCT02564692)

Learn more: GeneMatch   

Studies for participants with and without memory loss

Alzheimer’s Disease Core Center (ADCC) (NCT01421420)

Alzheimer's Disease Neuroimaging Initiative 3 (ADNI3) Protocol (NCT02854033)

Learn more: ADNI 3

Studies for participants with memory loss

Aware – A Study to Evaluate the Efficacy and Safety of ABBV-8E12 in Subjects with Early Alzheimer’s Disease (NCT02880956)

A Study of LY3303560 in Participants With Early Symptomatic Alzheimer's Disease (PERISCOPE-ALZ) (NCT03518073

Phase 2 Study of BIIB092 in Participants With Early Alzheimer's Disease (TANGO) (NCT03352557)

Safety and Efficacy Study of Gantenerumab in Participants With Early Alzheimer's Disease (NCT03443973)

Study of AGB101 in Mild Cognitive Impairment Due to Alzheimer's Disease (Hope4MCI) (NCT03486938)